From bloodjournal.hematologylibrary.org at Dana-Farber Cancer Institute on March 24, 2014. For personal use only: Prepublished online January 2, 2014; doi:blood

Source URL: michorlab.dfci.harvard.edu

• Genetics
• Biology
• Epigenetics
• DNA
• DNA methylation
• Methylation
• Carcinogenesis
• ATM serine/threonine kinase
• Germinal center B-cell like diffuse large B-cell lymphoma
• Methyltransferase
• DNA methyltransferase
• Draft:Epigenetics of male infertility

Impact of genetic dynamics and single-cell heterogeneity on development of nonstandard personalized medicine strategies for cancer Robert A. Beckmana,b,1, Gunter S. Schemmannc,d, and Chen-Hsiang Yeanga,e a Simons Center

Source URL: www2.unb.ca

Optimization of Dosing for EGFR-Mutant Non−Small Cell Lung Cancer with Evolutionary Cancer Modeling Juliann Chmielecki, et al. Sci Transl Med 3, 90ra59 (2011); DOI: scitranslmed

Source URL: michorlab.dfci.harvard.edu

• Quinazolines
• Lung cancer
• Amines
• Tyrosine kinase receptors
• Ethers
• T790M
• Erlotinib
• EGFR inhibitors
• Epidermal growth factor receptor
• Gefitinib
• Afatinib
• Targeted therapy

Evolution of Resistance to Targeted Anti-Cancer Therapies during Continuous and Pulsed Administration Strategies Jasmine Foo, Franziska Michor* Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New Y

Source URL: michorlab.dfci.harvard.edu

• RTT
• Chemotherapy
• Prostate cancer
• Drug resistance
• Cancer stem cell
• Cancer research
• Leukemia
• Cancer
• Breast cancer
• Radiation therapy
• Breast cancer management

Dose-Dependent Mutation Rates Determine Optimum Erlotinib Dosing Strategies for EGFR Mutant Non-Small Cell Lung Cancer Patients

Source URL: michorlab.dfci.harvard.edu

• Medicine
• Clinical medicine
• Cancer
• RTT
• Evolutionary biology
• Carcinogenesis
• Cancer treatments
• Oncology
• Chemotherapy
• Mutation
• Cancer stem cell
• Erlotinib

GROUP LEADER POSITIONS Institut Curie, Paris The Institut Curie (http://www.curie.fr) is a world-class multidisciplinary cancer research centre linked to an hospital. It combines research in cell biology, genetics, epige

Source URL: www.enbdc.org

• Epigenetics
• Biology
• Genetic mapping
• Cancer research
• Epigenome
• PSL Research University
• Curie Institute

Published OnlineFirst January 21, 2014; DOI: .CANT Integrated Systems and Technologies: Mathematical Oncology Cancer Research

Source URL: michorlab.dfci.harvard.edu

• Cancer
• Clinical medicine
• Health
• Oncology
• Breast cancer
• Metastatic breast cancer
• Metastasis
• Bone metastasis
• RTT
• Mouse models of breast cancer metastasis
• Cancer stem cell

SUBJECT AREAS: BIOPHYSICS CANCER ENGINEERING A physical sciences network

Source URL: michorlab.dfci.harvard.edu

• Biology
• Medicine
• Cell biology
• Cellular processes
• Cancer research
• Developmental biology
• Breast cancer
• Induced stem cells
• MDA-MB-468
• Hyaluronic acid
• CD44
• Cell migration

Good Cells Gone Bad Good Cells Gone Bad Developed by the Arizona Cancer Center at the University of Arizona WHAT IS CANCER?

Source URL: www.niehs.nih.gov

• Biology
• Medicine
• Health
• RTT
• Cancer cell
• Cancer
• Breast cancer
• Cell
• Prostate cancer
• The Hallmarks of Cancer
• Carcinogenesis

The Therapeutic Implications of Plasticity of the Cancer Stem Cell Phenotype Kevin Leder1, Eric C. Holland2, Franziska Michor1* 1 Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, and D

Source URL: michorlab.dfci.harvard.edu

• Biology
• Stem cells
• Biotechnology
• Induced stem cells
• Developmental biology
• Carcinogenesis
• Cancer stem cell
• Cellular differentiation
• Stem-cell therapy
• Neural stem cell
• Progenitor cell
• Cancer cell